acetamide, 2-chloro-N-(2,2,2-trifluoroethyl)-

acetamide, 2-chloro-N-(2,2,2-trifluoroethyl)- - Names and Identifiers

Name	2-Chloro-N-(2,2,2-trifluoroethyl)acetamide
Synonyms	2-Chloro-N-(2,2,2-trifluoroethyl)acetamide 2-chloro-N-(2,2,2-trifluoroethyl)acetamide 2-CgHLORO-N-(2,2,2-TRIFLUOROETHYL)ACETAMIDE AcetaMide, 2-chloro-N-(2,2,2-trifluoroethyl)- acetamide, 2-chloro-N-(2,2,2-trifluoroethyl)-
CAS	170655-44-4
InChI	InChI=1/C4H5ClF3NO/c5-1-3(10)9-2-4(6,7)8/h1-2H2,(H,9,10)

acetamide, 2-chloro-N-(2,2,2-trifluoroethyl)- - Physico-chemical Properties

Molecular Formula	C4H5ClF3NO
Molar Mass	175.54
Density	1.368
Boling Point	218 ºC
Flash Point	86 ºC
Vapor Presure	0.129mmHg at 25°C
pKa	11.89±0.46(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.377

acetamide, 2-chloro-N-(2,2,2-trifluoroethyl)- - Introduction

2-choro-n-(2,2,2-trifluoroethyl)acetamide is an organic compound. Its chemical formula is C4H6ClF3NO.

Nature:
-Appearance: 2-choro-n-(2,2,2-trifluoroethyl)acetamide is a colorless liquid.
-Solubility: It can be partially dissolved in water and can be miscible with many organic solvents.
-Stability: It is an unstable compound and prone to decomposition reactions.

Use:
2-choro-n-(2,2,2-trifluoroethyl)acetamide is mainly used as an important intermediate in organic synthesis. It can be used in the synthesis of pesticides, pharmaceuticals and other organic compounds.

Method:
2-choro-n-(2,2,2-trifluoroethyl)acetamide can be synthesized by the following steps:
1. First, under anhydrous conditions, dichloroacetic acid is reacted with 2,2, 2-trifluoroethanol to obtain trifluoroethyl dichloroacetate.
2. The obtained trifluoroethyl dichloroacetate is then reacted with ammonia to produce 2-Chloro-N-(2,2,2-trifluoroethyl)acetamide.

Safety Information:
2-Chloro-N-(2,2,2-trifluoroethyl)acetamide is an organic compound, which is harmful to human body. Necessary safety measures should be taken during Operation or contact to avoid direct contact with skin and eyes. In the process of operation and storage, to maintain good ventilation conditions. At the same time, in the process of handling and disposal, to comply with the relevant laws and regulations.

Last Update：2024-04-09 21:11:58